Beavis effect

In a sim­u­la­tion study, William D. Beav­is showed that the aver­age esti­mates of phe­no­typ­ic vari­ances asso­ci­at­ed with cor­rect­ly iden­ti­fied QTL were great­ly over­es­ti­mat­ed if only 100 prog­eny were eval­u­at­ed, slight­ly over­es­ti­mat­ed if 500 prog­eny were eval­u­at­ed, and fair­ly close to the actu­al mag­ni­tude when 1000 prog­eny were eval­u­at­ed.

(http://www.genetics.org/content/165/4/2259)

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